Dna Replication Pdf Lecture
Dna replication is semi conservative one strand from each of the initial two strands end up in a daughter strand each strand serves as a template for a new strand new strand is formed by complementary base pairing of the correct nucleotide plus formation of a phosphodiester bond.
Dna replication pdf lecture. Complementary base pairing produces semiconservative replication ðdouble helix unwinds ðeach strand acts as template ðcomplementary base pairing ensures that t signals addition of a on new strand and g signals addition of c ðtwo daughter helices produced after replication. Lecture 7 dna replication 1. Two types of conserved sequences are found at oric three repeats of 13 bp gatrctnttntttt and four. Lecture 6 chapter 9.
In e coli replication origin is called oric which consists of 245 base pair and contains dna sequences that are highly conserved among bacterial replication origin. 9 30 textbook chapter 16 material on midterm 1 and final image credit. Dna is semi conservative. Lecture notes on dna replication and protein synthesis.
A mechanism is required to release the strain created by local unwinding. View lecture 8 dna replication in cells pdf from bio misc at st. It also looks at some of the causes of dna damage and what failure of the repair mechanism can lead to. Pdf on sep 18 2018 tariku simion published dna replication find read and cite all the research you need on researchgate.
University of leicester bs2009 dna replication and repair 18 february 2010 page 1 dna replication and repair this lecture explores the mechanisms of dna replication and also the ways in which dna can repair any replication errors. One strand acts as a template because nucleotides are added at the 3 end of the growing strand dna synthesis proceeds in a 5 to 3 direction. Dna must be replicated so that the information it holds can be maintained and passed to future cell generations even as that information is accessed to guide the manufacture of proteins. Chem notes 6 pdf lecture 6 chapter 9 dna replication.
Dna replication begins from origin. Dna replication in prokaryotes. Transcription and translation dna structure dna or deoxyribonucleic acid a double helix nucleic acid often is compared to a twisted ladder with the rails of the ladder represented by the alternating deoxyribose and phosphate. A double helix separate into two single strands and each strand serves as a template on which complementary strand is synthesized.